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KMID : 0371420200980040190
Annals of Surgical Treatment and Research
2020 Volume.98 No. 4 p.190 ~ p.198
Drainage procedure for pancreatolithiasis: re-examination of the pancreatic duct diameter standard
Chen Guoyong

You Yu
Yan Hongxian
He Junchuang
Gong Jianping
Wei Sidong
Abstract
Purpose: Pancreatic duct decompression relieves pancreatic duct stone (PDS)-associated abdominal pain, though a consensus indication for the drainage procedure of the main pancreatic duct (MPD) is lacking. Moreover, major prognostic factors for postsurgical long-term pain relief and recurrence are largely unknown.

Methods: The clinical outcomes of 65 consecutive PDS patients undergoing surgery from 2008?2012 with 3+ years of follow-up were assessed.

Results: At postsurgical follow-up (median, 4.5 years; range, 3?7 years; procedure: Partington, n = 32; Frey, n = 27; pancreatoduodenectomy, n = 3; distal pancreatectomy, n = 3), the early complication and complete stone clearance rates were 29.2% and 97%, respectively. Long-term, complete and partial pain relief were 93.9%, 83.1%, and 10.8%, respectively. The risk of pancreatic fistula was higher in the <8 mm group than in the >8 mm group (P < 0.05), and 80% of the pancreatic fistula cases occurred in the <8 mm group. A shorter pain duration (P = 0.007), smaller MPD diameter (P = 0.04), and lower Izbicki pain score (P < 0.001) predicted long-term pain relief. Pain recurrence after initial remission occurred in 5 patients and was only related to pain duration (P = 0.02). Stone recurrence and pancreatic exocrine functional and endocrine functional deterioration occurred in 2, 5, and 11 patients, respectively.

Conclusion: Surgery provides excellent stone clearance, long-term pain relief, and acceptable postoperative morbidity. Using 8 mm as the criterion for drainage surgery can minimize the postoperative pancreatic fistula risk. Individualized and timely surgical treatment may improve the effect of surgery.
KEYWORD
Abdominal pain, Drainage, Operative surgical procedures, Pancreatitis, Prognosis
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